GB virus C in systemic medium- and small-vessel necrotizing vasculitides

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GB virus C in systemic medium- and small-vessel necrotizing vasculitides.

BACKGROUND Vasculitides are diseases of unknown origin in the majority of cases, but sometimes are the consequence of viral infections; for instance, hepatitis B virus (HBV)-related polyarteritis nodosa (PAN) or hepatitis C virus (HCV)-associated cryoglobulinaemia. OBJECTIVE To investigate the role of hepatitis G or GB virus C (GBV-C) in various forms of medium- and small-vessel vasculitides....

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Therapeutic strategies for systemic necrotizing vasculitides.

Treatments of vasculitides have progressed markedly over the past few decades. The first attempts to obtain better-adapted therapeutic strategies evaluated the indications of conventional drugs, and their abilities prolong survival and reduce the number of relapses, while decreasing the severity and number of side effects. Many prospective clinical trials were organized by the French Vasculitis...

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Clinical trials on systemic necrotizing vasculitides.

Treatments of systemic necrotizing vasculitides have progressed markedly over the past few decades. The first attempts to obtain better-adapted therapeutic strategies evaluated the indications of conventional drugs, and their abilities to prolong survival and prevent relapses, while decreasing the severity and number of side effects. Most of the prospective clinical trials were organized by the...

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Small-vessel and medium-vessel vasculitis.

Introduction The vasculitides include a broad spectrum of disorders that span a clinical spectrum from benign, self-limited disease to fulminant conditions that are fatal in the absence of therapy. Whereas the large-vessel vasculitides consist of 2 principal disorders, giant cell arteritis and Takayasu arteritis, the mediumand small-vessel vasculitides are much more diverse, including multiple ...

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Virus-induced Systemic Vasculitides: New Therapeutic Approaches

The best therapeutic strategy in virus-induced vasculitides should take into account the etiology of the disease and be adapted to the pathogenesis. The combination of antiviral treatments and plasma exchanges has been proven effective in polyarteritis nodosa (PAN). In human immunodeficiency virus (HIV)-related vasculitis this strategy is also effective and does not jeopardize, like cytotoxic a...

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ژورنال

عنوان ژورنال: Rheumatology

سال: 1998

ISSN: 1460-2172

DOI: 10.1093/rheumatology/37.12.1292